The world has changed, the human and vampire races live together on a daily basis. The blood that vampires drink is artificial. They no longer go out hunting and their blood becomes precious because it preserves human life for much longer.
A group of recent grads head out on a late night drive for grub, hoping to enjoy one final hangout before their paths diverge. Instead, they accidentally turn onto a never-ending, two-lane hellscape surrounded by untold horrors and cosmic forces beyond th