Cheech must deal with losing his job, his angry neighbor, and trying to score with sexy Donna. Meanwhile, Chong meets Cheech's cousin Red and the two have a wild time in Hollywood with a big bag of buds and a cool Ferrari. Along the way they meet everyone from Pee Wee Herman to really cool aliens.
It tells the story of a therapy group that is forced to confront the monsters of their past when an isolated weekend retreat tests their emotional resilience and ability to survive.