California gold rush, late 1800's: A gun slinging bounty hunter (Mortimer) travels deep into the mountains to find a deadly Apache warrior (Brother Wolf) who is wanted by the law. Along the way he passes through a gold mining Town. The miners help direct Mortimer to the Apache and send him on his way.
Mortimer enters the forest and begins to track the Apache. Back in town, the miners un-earth an ancient meteor. They use their pick axes to crack it open. A section of the meteor splits apart and spores explode out of it. The spore surround and infect the entire population of the mining camp. They are transformed into ravenous mutants.
After a vicious battle against the Apache warrior, Mortimer exits the forest with his prisoner in shackles. They hike back to the mining town to find them selves surrounded by a horde of blood thirsty mutants. Now Mortimer the gun slinger and Brother Wolf the Warrior must join together to survive the mutant hordes. What ensues is a bloodbath of horror for the Dead and the Damned.
亚历克斯(伊万•麦克格雷格 Ewan McGregor 饰)、大卫(克里斯托弗•埃克莱斯顿 Christopher Eccleston 饰)和朱丽叶(凯瑞•福克斯 Kerry Fox 饰)三个好友合住在一户公寓内,三人征集新房客时问出各种怪异问题,玩的不亦乐乎,最后在朱丽叶主张下,吸纳了写作的单身男子雨果,岂料雨果入住不久就身亡在屋内,惊慌的三人发现了雨果装有巨额现金的箱子,金钱诱惑难以抵御,他们悄悄将雨果分尸掩埋。巨款在手的亚历克斯和朱丽叶春风得意,但会计员大卫却终日忧心忡忡,终于大卫在二人挥霍钱财后暴发,将钱箱搬到阁楼收藏看管。与此同时,两名匪徒为了寻找钱箱,一路大开杀戒,并闯入了三人的公寓,大卫突然发力将匪徒杀死,此时的大卫,已经愈发神经质,将事情引向了更加危险的方向……
查理(哈威·凯特尔 Harvey Keitel 饰)和意大利移民朋友们混迹在纽约曼哈顿的下东区,没有固定职业,靠着替黑手党卖命混口饭吃。查理的好友乔尼(罗伯特·德尼罗 Robert De Niro 饰)欠了黑市商人迈克尔的钱,却无力偿还,整日被追债。查理与乔尼的表妹特丽莎真心相爱,但是特丽莎希望他能离开这种不稳定的生活,去寻找新生活。迈克尔因为找乔尼要不到钱而恼羞成怒,查理为了帮乔尼摆平此事,承诺他会尽早还钱。在酒吧里,迈克尔发现乔尼已经穷到极致,根本就不可能还钱时,两人扭打在一起。失控的乔尼拔枪瞄准迈克尔,逼退了迈克尔。为了躲避迈克尔的报复,查理、乔尼、特丽莎三人决定躲到乡下去,他们在开车去看电影的路上,一辆汽车从后面追上来。车里正是迈克尔,他拔出手枪向三人的车子开火。汽车被撞翻了,受伤的三人,艰难地从车中爬出,面对茫茫黑夜,他们发出了无望的哭喊。